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Human-Identical Milk Oligosaccharides in Infant Formula: How Close Are We to Evidence-Based Benefit?

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

Media 1.png
Like

Human-Identical Milk Oligosaccharides in Infant Formula: How Close Are We to Evidence-Based Benefit?

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

Media 1.png
Like

Human-Identical Milk Oligosaccharides in Infant Formula: How Close Are We to Evidence-Based Benefit?

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

Published at Advances in Nutrition | Editorial

Written by Yarden Golan | 2026

The Latest

The Latest

Genomic characterization of normal and aberrant human milk production

Written by Golan, Y., Nyquist, S. K., Liu, Z., Ennis, D., Zhao, J., Blair, E., Khan, A. R., et al.

Published at Science Advances

2025

Methods for Preserving Human Milk Cellular and Milk Fat Globule RNA

Written by Li, Z., Fischbein, N., Jin, F., Nyquist, S.K., O’Brien, K., Ahituv, N., Flaherman, V., Golan, Y

Published at J Mammary Gland Biol Neoplasia

2026

Human-Identical Milk Oligosaccharides in Infant Formula: How Close Are We to Evidence-Based Benefit?

Written by Yarden Golan

Published at Advances in Nutrition

2026

Filter
Like

Human-identical milk oligosaccharides in infant formula: How close are we to evidence-based benefit?

Golan, Y.

Advances in Nutrition 2026;100612

2026

Like

Integrating Biological, Behavioral, and Economic Factors in the Practice and Study of Early, Unplanned Lactation Cessation

Bookhart, L.H., Devane-Johnson, S., Esquerra-Zwiers, A., Golan Maor, Y., Gomez, J., Kivlighan, K.T., Medina Poeliniz, C., Walker, R., Johnson, T.J., Parker, L.A.

Breastfeeding Med 20, 460–469

2025

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Effects of vaccination against influenza, pertussis, and COVID-19 on human milk antibodies: current evidence and implications for health equity

Hunagund, S.*, Golan, Y.*, Asiodu, I.V., Prahl, M., Gaw, S.L.

Front Immunol

2022

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Genetic and Physiological Factors Affecting Human Milk Production and Composition

Golan, Y., Assaraf, Y.G.

Nutrients 12, 1500

2020

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The role of the zinc transporter SLC30A2/ZnT2 in health and disease

Golan, Y., Kambe, T., and Assaraf, Y. G.

Metallomics

2017

Like

Methods for Preserving Human Milk Cellular and Milk Fat Globule RNA

Li, Z., Fischbein, N., Jin, F., Nyquist, S.K., O’Brien, K., Ahituv, N., Flaherman, V., Golan, Y.

J Mammary Gland Biol Neoplasia

2026

Like

Genomic characterization of normal and aberrant human milk production

Golan, Y., Nyquist, S. K., Liu, Z., Ennis, D., Zhao, J., Blair, E., Khan, A. R., et al.

Science Advances, 11(37), eadr7174

2025

Like

Maternal Complications of Pregnancy and Achievement of Secretory Activation and Coming to Volume in Breast Pump-Dependent Mothers of Preterm Infants

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Breastfeed Med 20, 512–520

2025

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Pregnancy and lactation induce distinct immune responses to COVID-19 booster vaccination and SARS-CoV-2 breakthrough infection

Yin, K., Li, L., Luo, X., Neidleman, J., Cassidy, A.G., Golan, Y., Ozarslan, N., Lin, C.Y., Jigmeddagva, U., Ilala, M., Chidboy, M.A., Prahl, M., Gaw, S.L., Roan, N.R.

JCI Insight 10, e191930

2025

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Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy

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npj Vaccines 9, 156.

2024

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Assessment of Adverse Reactions, Antibody Patterns, and 12-month Outcomes in the Mother-Infant Dyad After COVID-19 mRNA Vaccination in Pregnancy

Cassidy, A.G., Li, L., Golan, Y., Gay, C., Lin, C.Y., Jigmeddagva, U., Chidboy, M.A., Ilala, M., Buarpung, S., Gonzalez, V.J., et al.

JAMA Netw Open 6, e2323405–e2323405

2023

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Nirmatrelvir–Ritonavir (Paxlovid) for Mild Coronavirus Disease 2019 (COVID-19) in Pregnancy and Lactation

Lin, C. Y., Cassidy, A. G., Li, L., Prahl, M., Golan, Y., Gaw, S. L.

Obstet Gynecol 2023;141:957–60.

2023

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Milk antibody response after 3rd dose of COVID-19 mRNA vaccine and SARS-CoV-2 breakthrough infection and implications for infant protection

Golan, Y., Ilala, M., Gay, C., Hunagund, S., Lin, C. Y., Cassidy, A. G., Jigmeddagva, U., Li, L., Ozarslan, N., Asiodu, I. V., Ahituv, N., Flaherman, V. J., Gaw, S. L., & Prahl, M.

iScience, 26(10), 107767

2023

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Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy

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Nature Communications, 13(1), 4422

2022

Like

Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination

Matsui, Y., Li, L., Prahl, M., Cassidy, A. G., Ozarslan, N., Golan, Y., Gonzalez, V. J., Lin, C. Y., Jigmeddagva, U., Chidboy, M. A., Montano, M., Taha, T. Y., Khalid, M. M., Sreekumar, B., Hayashi, J. M., Chen, P.-Y., Kumar, G. R., Warrier, L., Wu, A. H., … Gaw, S. L.

JCI Insight, 7(12)

2022

Like

Cellular and transcriptional diversity over the course of human lactation

Nyquist, S.K., Gao, P., Haining, T.K.J., Retchin, M.R., Golan, Y., Drake, R.S., Kolb, K., Mead, B.E., Ahituv, N., Martinez, M.E., et al.

Proc. Natl. Acad. Sci. 119

2022

Like

Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses

Sievers, B.L., Chakraborty, S., Xue, Y., Gelbart, T., Gonzalez, J.C., Cassidy, A.G., Golan, Y., Prahl, M., Gaw, S.L., Arunachalam, P.S., et al.

Sci. Transl. Med. 14, 7842

2022

Like

Evaluating COVID-19 Vaccine-Related Messenger RNA in Breast Milk—Reply

Golan, Y., Flaherman, V.J., and Gaw, S.L.

JAMA Pediatr. 176, 100–101

2022

Like

In situ dimerization of multiple wild type and mutant zinc transporters in live cells using bimolecular fluorescence complementation.

Lasry, I.*, Golan, Y.*, Berman, B., Amram, N., Glaser, F., and Assaraf, Y. G.

The Journal of Biological Chemistry 289, 7275-7292.

2014

Like

COVID-19 mRNA Vaccination in Lactation: Assessment of adverse events and vaccine related antibodies in mother-infant dyads

Golan, Y., Prahl, M., Cassidy, A., et al.

Front. Immunol

2021

Like

Evaluation of Messenger RNA From COVID-19 BTN162b2 and mRNA-1273 Vaccines in Human Milk

Golan, Y., Prahl, M., Cassidy, A., Lin, C. Y., Ahituv, N., Flaherman, V. J., Gaw, S. L.

JAMA Pediatr

2021

Like

Alterations in ZnT1 expression and function lead to impaired intracellular zinc homeostasis in cancer.

Lehvy, AI., Horev, G., Golan, Y., Glaser, F., Shammai, Y., Assaraf, YG.

Cell Death Discov 5, 144.

2019

Like

High proportion of transient neonatal zinc deficiency (TNZD) causing alleles in the general population

Golan, Y.,* Lehvy, A.,*, Horev, G., and Assaraf, Y. G.

J Cell Mol Med. 2018 Nov 18.

2018

Like

ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion.

Golan, Y., Alhadeff, R. , Warshel, A., and Assaraf, Y. G.

PLoS Comput. Biol. 15(3): e1006882

2019

Like

Demonstrating aspects of multiscale modeling by studying the permeation pathway of the human ZnT2 zinc transporter

Golan, Y.,* Alhadeff, R.,*, Glaser F., Ganoth, A., Warshel A., and Assaraf, Y. G.

PLoS Comput. Biol. 2018;14: e1006503

2018

Like

Identification of genetic diseases using breast milk cell analysis: The case of transient neonatal zinc deficiency (TNZD)

Golan, Y., Yerushalmi B., Efrati, E., and Assaraf, Y. G.

Cell. Mol. Med. Open Access 2017; 3(2): 8

2017

Like

Molecular basis of transient neonatal zinc deficiency: Novel ZnT2 mutations disrupting zinc binding and permeation

Golan, Y.,* Itsumura, N.,* Glaser, F., Berman, B., Kambe, T., and Assaraf, Y. G.

The Journal of Biological Chemistry 291, 13546-13559.

2016

Like

Heterodimerization, altered subcellular localization, and function of multiple zinc transporters in viable cells using bimolecular fluorescence complementation.

Golan, Y., Berman, B., and Assaraf, Y. G.

The Journal of Biological Chemistry 290, 9050-9063.

2015

Filter
Like
Human-identical milk oligosaccharides in infant formula: How close are we to evidence-based benefit?

Golan, Y.

2026

Advances in Nutrition 2026;100612

Like
Integrating Biological, Behavioral, and Economic Factors in the Practice and Study of Early, Unplanned Lactation Cessation

Bookhart, L.H., Devane-Johnson, S., Esquerra-Zwiers, A., Golan Maor, Y., Gomez, J., Kivlighan, K.T., Medina Poeliniz, C., Walker, R., Johnson, T.J., Parker, L.A.

2025

Breastfeeding Med 20, 460–469

Like
Effects of vaccination against influenza, pertussis, and COVID-19 on human milk antibodies: current evidence and implications for health equity

Hunagund, S.*, Golan, Y.*, Asiodu, I.V., Prahl, M., Gaw, S.L.

2022

Front Immunol

Like
Genetic and Physiological Factors Affecting Human Milk Production and Composition

Golan, Y., Assaraf, Y.G.

2020

Nutrients 12, 1500

Like
The role of the zinc transporter SLC30A2/ZnT2 in health and disease

Golan, Y., Kambe, T., and Assaraf, Y. G.

2017

Metallomics

Like
Methods for Preserving Human Milk Cellular and Milk Fat Globule RNA

Li, Z., Fischbein, N., Jin, F., Nyquist, S.K., O’Brien, K., Ahituv, N., Flaherman, V., Golan, Y.

2026

J Mammary Gland Biol Neoplasia

Like
Genomic characterization of normal and aberrant human milk production

Golan, Y., Nyquist, S. K., Liu, Z., Ennis, D., Zhao, J., Blair, E., Khan, A. R., et al.

2025

Science Advances, 11(37), eadr7174

Like
Maternal Complications of Pregnancy and Achievement of Secretory Activation and Coming to Volume in Breast Pump-Dependent Mothers of Preterm Infants

Hoban, R., Pei, Q., Medina Poeliniz, C., Golan Maor, Y., Walker, R.E., Meier, P.P., Monk, A., Parker, L.A.

2025

Breastfeed Med 20, 512–520

Like
Pregnancy and lactation induce distinct immune responses to COVID-19 booster vaccination and SARS-CoV-2 breakthrough infection

Yin, K., Li, L., Luo, X., Neidleman, J., Cassidy, A.G., Golan, Y., Ozarslan, N., Lin, C.Y., Jigmeddagva, U., Ilala, M., Chidboy, M.A., Prahl, M., Gaw, S.L., Roan, N.R.

2025

JCI Insight 10, e191930

Like
Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy

Li, L., Matsui, Y., Prahl, M.K., Cassidy, A.G., Golan, Y., et al.

2024

npj Vaccines 9, 156.

Like
Assessment of Adverse Reactions, Antibody Patterns, and 12-month Outcomes in the Mother-Infant Dyad After COVID-19 mRNA Vaccination in Pregnancy

Cassidy, A.G., Li, L., Golan, Y., Gay, C., Lin, C.Y., Jigmeddagva, U., Chidboy, M.A., Ilala, M., Buarpung, S., Gonzalez, V.J., et al.

2023

JAMA Netw Open 6, e2323405–e2323405

Like
Nirmatrelvir–Ritonavir (Paxlovid) for Mild Coronavirus Disease 2019 (COVID-19) in Pregnancy and Lactation

Lin, C. Y., Cassidy, A. G., Li, L., Prahl, M., Golan, Y., Gaw, S. L.

2023

Obstet Gynecol 2023;141:957–60.

Like
Milk antibody response after 3rd dose of COVID-19 mRNA vaccine and SARS-CoV-2 breakthrough infection and implications for infant protection

Golan, Y., Ilala, M., Gay, C., Hunagund, S., Lin, C. Y., Cassidy, A. G., Jigmeddagva, U., Li, L., Ozarslan, N., Asiodu, I. V., Ahituv, N., Flaherman, V. J., Gaw, S. L., & Prahl, M.

2023

iScience, 26(10), 107767

Like
Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy

Prahl, M., Golan, Y., Cassidy, A. G., Matsui, Y., Li, L., Alvarenga, B., Chen, H., Jigmeddagva, U., Lin, C. Y., Gonzalez, V. J., Chidboy, M. A., Warrier, L., Buarpung, S., Murtha, A. P., Flaherman, V. J., Greene, W. C., Wu, A. H. B., Lynch, K. L., Rajan, J., & Gaw, S. L.

2022

Nature Communications, 13(1), 4422

Like
Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination

Matsui, Y., Li, L., Prahl, M., Cassidy, A. G., Ozarslan, N., Golan, Y., Gonzalez, V. J., Lin, C. Y., Jigmeddagva, U., Chidboy, M. A., Montano, M., Taha, T. Y., Khalid, M. M., Sreekumar, B., Hayashi, J. M., Chen, P.-Y., Kumar, G. R., Warrier, L., Wu, A. H., … Gaw, S. L.

2022

JCI Insight, 7(12)

Like
Cellular and transcriptional diversity over the course of human lactation

Nyquist, S.K., Gao, P., Haining, T.K.J., Retchin, M.R., Golan, Y., Drake, R.S., Kolb, K., Mead, B.E., Ahituv, N., Martinez, M.E., et al.

2022

Proc. Natl. Acad. Sci. 119

Like
Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses

Sievers, B.L., Chakraborty, S., Xue, Y., Gelbart, T., Gonzalez, J.C., Cassidy, A.G., Golan, Y., Prahl, M., Gaw, S.L., Arunachalam, P.S., et al.

2022

Sci. Transl. Med. 14, 7842

Like
Evaluating COVID-19 Vaccine-Related Messenger RNA in Breast Milk—Reply

Golan, Y., Flaherman, V.J., and Gaw, S.L.

2022

JAMA Pediatr. 176, 100–101

Like
In situ dimerization of multiple wild type and mutant zinc transporters in live cells using bimolecular fluorescence complementation.

Lasry, I.*, Golan, Y.*, Berman, B., Amram, N., Glaser, F., and Assaraf, Y. G.

2014

The Journal of Biological Chemistry 289, 7275-7292.

Like
COVID-19 mRNA Vaccination in Lactation: Assessment of adverse events and vaccine related antibodies in mother-infant dyads

Golan, Y., Prahl, M., Cassidy, A., et al.

2021

Front. Immunol

Like
Evaluation of Messenger RNA From COVID-19 BTN162b2 and mRNA-1273 Vaccines in Human Milk

Golan, Y., Prahl, M., Cassidy, A., Lin, C. Y., Ahituv, N., Flaherman, V. J., Gaw, S. L.

2021

JAMA Pediatr

Like
Alterations in ZnT1 expression and function lead to impaired intracellular zinc homeostasis in cancer.

Lehvy, AI., Horev, G., Golan, Y., Glaser, F., Shammai, Y., Assaraf, YG.

2019

Cell Death Discov 5, 144.

Like
High proportion of transient neonatal zinc deficiency (TNZD) causing alleles in the general population

Golan, Y.,* Lehvy, A.,*, Horev, G., and Assaraf, Y. G.

2018

J Cell Mol Med. 2018 Nov 18.

Like
ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion.

Golan, Y., Alhadeff, R. , Warshel, A., and Assaraf, Y. G.

2019

PLoS Comput. Biol. 15(3): e1006882

Like
Demonstrating aspects of multiscale modeling by studying the permeation pathway of the human ZnT2 zinc transporter

Golan, Y.,* Alhadeff, R.,*, Glaser F., Ganoth, A., Warshel A., and Assaraf, Y. G.

2018

PLoS Comput. Biol. 2018;14: e1006503

Like
Identification of genetic diseases using breast milk cell analysis: The case of transient neonatal zinc deficiency (TNZD)

Golan, Y., Yerushalmi B., Efrati, E., and Assaraf, Y. G.

2017

Cell. Mol. Med. Open Access 2017; 3(2): 8

Like
Molecular basis of transient neonatal zinc deficiency: Novel ZnT2 mutations disrupting zinc binding and permeation

Golan, Y.,* Itsumura, N.,* Glaser, F., Berman, B., Kambe, T., and Assaraf, Y. G.

2016

The Journal of Biological Chemistry 291, 13546-13559.

Like
Heterodimerization, altered subcellular localization, and function of multiple zinc transporters in viable cells using bimolecular fluorescence complementation.

Golan, Y., Berman, B., and Assaraf, Y. G.

2015

The Journal of Biological Chemistry 290, 9050-9063.

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